abstract：:Glial cell-derived neurotrophic factor (GDNF) has shown beneficial effects in models of Parkinson's disease. The mild results observed in the double-blind clinical trial by intraputamenal infusion of recombinant GDNF proteins warrant a search for alternative delivery methods. In this study, we investigated the functio...

journal_title：Scientific reports

authors： Ren Z,Wang J,Wang S,Zou C,Li X,Guan Y,Chen Z,Zhang YA

更新日期：2013-09-27 00:00:00

abstract：:Topological phase transition is accompanied with a change of topological numbers. According to the bulk-edge correspondence, the gap closing and the breakdown of the adiabaticity are necessary at the phase transition point to make the topological number ill-defined. However, the gap closing is not always needed. In th...

journal_title：Scientific reports

authors： Ezawa M,Tanaka Y,Nagaosa N

更新日期：2013-09-27 00:00:00

abstract：:The generation of novelty is central to any creative endeavor. Novelty generation and the relationship between novelty and individual hedonic value have long been subjects of study in social psychology. However, few studies have utilized large-scale datasets to quantitatively investigate these issues. Here we consider...

journal_title：Scientific reports

authors： Sreenivasan S

更新日期：2013-09-26 00:00:00

abstract：:Quantum entanglement can help to increase the precision of optical phase measurements beyond the shot noise limit (SNL) to the ultimate Heisenberg limit. However, the N-photon parity measurements required to achieve this optimal sensitivity are extremely difficult to realize with current photon detection technologies,...

journal_title：Scientific reports

authors： Xiang GY,Hofmann HF,Pryde GJ

更新日期：2013-09-25 00:00:00

abstract：:A common philosophy in control theory is the control of disorder by order. Control of decoherence is no exception; strategies aimed at suppressing quantum decoherence adopt this point of view. Here we predict an anomalous phenomenon in open quantum systems-control of disorder by (even more) disorder. It is shown that ...

journal_title：Scientific reports

authors： Jing J,Wu LA

更新日期：2013-09-25 00:00:00

abstract：:High sensitivity magnetoelectric sensors with their electromechanical resonance frequencies < 200 kHz have been recently demonstrated using magnetostrictive/piezoelectric magnetoelectric heterostructures. In this work, we demonstrate a novel magnetoelectric nano-electromechanical systems (NEMS) resonator with an elect...

journal_title：Scientific reports

authors： Nan T,Hui Y,Rinaldi M,Sun NX

更新日期：2013-01-01 00:00:00

abstract：:An accurate and efficient solution of the radiative transport equation is proposed for modeling the propagation of photons in the three-dimensional anisotropically scattering half-space medium. The exact refractive index mismatched boundary condition is considered and arbitrary rotationally invariant scattering functi...

journal_title：Scientific reports

authors： Liemert A,Kienle A

更新日期：2013-01-01 00:00:00

abstract：:Faces presented upside-down are harder to recognize than presented right-side up, an effect known as the face inversion effect. With inversion the perceptual processing of the spatial relationship among facial parts is disrupted. Previous literature indicates a face inversion effect in chimpanzees toward familiar and ...

journal_title：Scientific reports

authors： Dahl CD,Rasch MJ,Tomonaga M,Adachi I

更新日期：2013-01-01 00:00:00

abstract：:The migration of oligodendrocyte progenitor cells (OPCs) to the white matter is an indispensable requirement for an intact brain function. The mechanism of cell migration in general is not yet completely understood. Nevertheless, evidence is accumulating that besides the coordinated rearrangement of the cytoskeleton, ...

journal_title：Scientific reports

authors： Happel P,Möller K,Schwering NK,Dietzel ID

更新日期：2013-01-01 00:00:00

abstract：:Crypt neurons are a third type of olfactory receptor neurons with a highly unusual "one cell type--one receptor" mode of expression, the same receptor being expressed by the entire population of crypt neurons. Attempts to identify the target region(s) of crypt neurons have been inconclusive so far. We report that TrkA...

journal_title：Scientific reports

authors： Ahuja G,Ivandic I,Saltürk M,Oka Y,Nadler W,Korsching SI

更新日期：2013-01-01 00:00:00

abstract：:Bacterial cell wall is targeted by many antibiotics. Among them are lantibiotics, which realize their function via interaction with plasma membrane lipid-II molecule - a chemically conserved part of the cell wall synthesis pathway. To investigate structural and dynamic properties of this molecule, we have performed a ...

journal_title：Scientific reports

authors： Chugunov A,Pyrkova D,Nolde D,Polyansky A,Pentkovsky V,Efremov R

更新日期：2013-01-01 00:00:00

abstract：:Emerging concepts for on-chip biotechnologies aim to replace microfluidic flow by active, molecular-motor driven transport of cytoskeletal filaments, including applications in bio-simulation, biocomputation, diagnostics, and drug screening. Many of these applications require reliable detection, with minimal data acqui...

journal_title：Scientific reports

authors： Lard M,ten Siethoff L,Månsson A,Linke H

更新日期：2013-01-01 00:00:00

abstract：:Phosphorylation plays important roles in several processes including synaptic plasticity and memory. The critical role of extracellular signal-regulated kinase (ERK) in these processes is well established. ERK is activated in a sustained manner by different stimuli. However, the mechanisms of sustained ERK activation ...

journal_title：Scientific reports

authors： Maharana C,Sharma KP,Sharma SK

更新日期：2013-01-01 00:00:00

abstract：:Photoacoustic tomography (PAT) offers three-dimensional (3D) structural and functional imaging of living biological tissue with label-free, optical absorption contrast. These attributes lend PAT imaging to a wide variety of applications in clinical medicine and preclinical research. Despite advances in live animal ima...

journal_title：Scientific reports

authors： Xiang L,Wang B,Ji L,Jiang H

更新日期：2013-01-01 00:00:00

abstract：:We analyze the entire publication database of the American Physical Society generating longitudinal (50 years) citation networks geolocalized at the level of single urban areas. We define the knowledge diffusion proxy, and scientific production ranking algorithms to capture the spatio-temporal dynamics of Physics know...

journal_title：Scientific reports

authors： Zhang Q,Perra N,Gonçalves B,Ciulla F,Vespignani A

更新日期：2013-01-01 00:00:00

abstract：:This work reports the remarkable effect of reversible gas molecular sieving for high temperature gas separation from cobalt doped ethoxy polysiloxane (CoES40) membranes. This effect stemmed from alternating the reducing and oxidising (redox) state of the cobalt particles embedded in the ES40 matrix. The reduced membra...

journal_title：Scientific reports

authors： Miller CR,Wang DK,Smart S,Diniz da Costa JC

更新日期：2013-01-01 00:00:00

abstract：:Rapid facial mimicry (RFM) is an automatic response, in which individuals mimic others' expressions. RFM, only demonstrated in humans and apes, is grounded in the automatic perception-action coupling of sensorimotor information occurring in the mirror neuron system. In humans, RFM seems to reflect the capacity of indi...

journal_title：Scientific reports

authors： Mancini G,Ferrari PF,Palagi E

更新日期：2013-01-01 00:00:00

abstract：:Toward the increasing demands of portable energy storage and electric vehicle applications, the widely used graphite anodes with significant drawbacks become more and more unsuitable. Herein, we report a novel scaffold of hierarchical silicon nanowires-carbon textiles anodes fabricated via a facile method. Further, co...

journal_title：Scientific reports

authors： Liu B,Wang X,Chen H,Wang Z,Chen D,Cheng YB,Zhou C,Shen G

更新日期：2013-01-01 00:00:00

abstract：:The characterization of network community structure has profound implications in several scientific areas. Therefore, testing the algorithms developed to establish the optimal division of a network into communities is a fundamental problem in the field. We performed here a highly detailed evaluation of community detec...

journal_title：Scientific reports

authors： Aldecoa R,Marín I

更新日期：2013-01-01 00:00:00

abstract：:Solving the crystal structure of Cbl(TKB) in complex with a pentapeptide, pYTPEP, revealed that the PEP region adopted a poly-L-proline type II (PPII) helix. An unnatural amino acid termed a proline-templated glutamic acid (ptE) that constrained both the backbone and sidechain to the bound conformation was synthesized...

journal_title：Scientific reports

authors： Kumar EA,Chen Q,Kizhake S,Kolar C,Kang M,Chang CE,Borgstahl GE,Natarajan A

更新日期：2013-01-01 00:00:00

abstract：:The Vacuole Membrane Protein 1 -VMP1- is a pancreatitis-associated transmembrane protein whose expression triggers autophagy in several human diseases. In the current study, we unveil the mechanism through which this protein induces autophagosome formation in mammalian cells. We show that VMP1 autophagy-related functi...

journal_title：Scientific reports

authors： Molejon MI,Ropolo A,Re AL,Boggio V,Vaccaro MI

更新日期：2013-01-01 00:00:00

abstract：:While chromatin modifications can offer a useful readout for enhancer activities, it is less clear whether these modification marks are a cause or consequence of transcription factor occupancy and enhancer activation. We have examined in details the temporal events of acetyltransferase associations and histone acetyla...

journal_title：Scientific reports

authors： Hamed M,Khilji S,Chen J,Li Q

更新日期：2013-01-01 00:00:00

abstract：:Solid oxide fuel cells (SOFC) are the cleanest, most efficient, and cost-effective option for direct conversion to electricity of a wide variety of fuels. While significant progress has been made in anode materials with enhanced tolerance to coking and contaminant poisoning, cathodic polarization still contributes con...

journal_title：Scientific reports

authors： Choi S,Yoo S,Kim J,Park S,Jun A,Sengodan S,Kim J,Shin J,Jeong HY,Choi Y,Kim G,Liu M

更新日期：2013-01-01 00:00:00

abstract：:Methylacetoin (3-hydroxy-3-methylbutan-2-one) and 2-methyl-2,3-butanediol are currently obtained exclusively via chemical synthesis. Here, we report, to the best of our knowledge, the first alternative route, using engineered Escherichia coli. The biological synthesis of methylacetoin was first accomplished by reversi...

journal_title：Scientific reports

authors： Jiang X,Zhang H,Yang J,Zheng Y,Feng D,Liu W,Xu X,Cao Y,Zou H,Zhang R,Cheng T,Jiao F,Xian M

更新日期：2013-01-01 00:00:00

abstract：:Glioblastoma multiforme (GBM) is a highly invasive and chemoradioresistant brain malignancy. Temozolomide (TMZ), a DNA-alkylating agent, is effective against GBM and has become the standard first-line drug. However, the mechanism by which TMZ regulates the progression of GBM remains elusive. Here, we demonstrate that ...

journal_title：Scientific reports

authors： Yamaki T,Suenaga Y,Iuchi T,Alagu J,Takatori A,Itami M,Araki A,Ohira M,Inoue M,Kageyama H,Yokoi S,Saeki N,Nakagawara A

更新日期：2013-01-01 00:00:00

abstract：:The new era of spintronics promises the development of nanodevices, where the electron spin will be used to store information and charge currents will be replaced by spin currents. For this, ferromagnetic semiconductors at room temperature are needed. We report on significant room-temperature spin polarization of EuS ...

journal_title：Scientific reports

authors： Pappas SD,Poulopoulos P,Lewitz B,Straub A,Goschew A,Kapaklis V,Wilhelm F,Rogalev A,Fumagalli P

更新日期：2013-01-01 00:00:00

abstract：:Triboelectric charging is common in desert sandstorms and dust devils on Earth; however, it remains poorly understood. Here we show a charging mechanism of sands with the adsorbed water on micro-porous surface in wind-blown sand based on the fact that water content is universal but usually a minor component in most pa...

journal_title：Scientific reports

authors： Gu Z,Wei W,Su J,Yu CW

更新日期：2013-01-01 00:00:00

abstract：:Application of PCR to multiplexing assays is not trivial; it requires multiple fluorescent labels for amplicon detection and sophisticated software for data interpretation. Alternative PCR-free methods exploiting new concepts in nanotechnology exhibit high sensitivities but require multiple labeling and/or amplificati...

journal_title：Scientific reports

authors： Papadakis G,Tsortos A,Kordas A,Tiniakou I,Morou E,Vontas J,Kardassis D,Gizeli E

更新日期：2013-01-01 00:00:00

abstract：:This work reports the first study of current-driven magnetization noise in a single, nanometerscale, ferromagnetic (Co) particle, attached to normal metal leads by high-resistance tunneling junctions. As the tunnel current increases at low temperature, the magnetic switching field decreases, its probability distributi...

journal_title：Scientific reports

authors： Jiang W,Birk FT,Davidović D

更新日期：2013-01-01 00:00:00

abstract：:The strange three-dimensional flight behaviour of slowly spinning soccer balls is one of the most interesting and unknown phenomenon associated with the trajectories of sports balls. Many spectators have experienced numerous exciting and emotional instances while observing the curious flight behaviour of these balls. ...

journal_title：Scientific reports

authors： Mizota T,Kurogi K,Ohya Y,Okajima A,Naruo T,Kawamura Y

更新日期：2013-01-01 00:00:00

abstract：:Non-compressible hemorrhage is the most common preventable cause of death on battlefield and in civilian traumatic injuries. We report the use of microsecond pulses of electric current to induce rapid constriction in femoral and mesenteric arteries and veins in rats. Electrically-induced vasoconstriction could be indu...

journal_title：Scientific reports

authors： Mandel Y,Manivanh R,Dalal R,Huie P,Wang J,Brinton M,Palanker D

更新日期：2013-01-01 00:00:00

abstract：:Focusing on the chemical basis of dietary selection while investigating the nutritional ecology of animals helps understand their feeding biology. It is also important to consider food abundance/biomass while studying the mechanism of animal food selection. We studied leaf selection in two Bornean folivorous primates ...

journal_title：Scientific reports

authors： Matsuda I,Tuuga A,Bernard H,Sugau J,Hanya G

更新日期：2013-01-01 00:00:00

abstract：:Haber-Bosch nitrogen (N) has been increasingly used in industrial products, e.g., nylon, besides fertilizer. Massive numbers of species of industrial reactive N (Nr) have emerged and produced definite consequences but receive little notice. Based on a comprehensive inventory, we show that (1) the industrial N flux has...

journal_title：Scientific reports

authors： Gu B,Chang J,Min Y,Ge Y,Zhu Q,Galloway JN,Peng C

更新日期：2013-01-01 00:00:00

abstract：:It remains a grand challenge to achieve both high activity and durability in Pt electrocatalysts for oxygen reduction reaction (ORR) in fuel cells. Here we develop a class of Pt highly concave cubic (HCC) nanocrystals, which are enriched with high-index facets, to enable high ORR activity. The durability of HCC nanocr...

journal_title：Scientific reports

authors： Wang C,Ma L,Liao L,Bai S,Long R,Zuo M,Xiong Y

更新日期：2013-01-01 00:00:00

abstract：:We report a daily-updated sequenced/species Tree Of Life (sTOL) as a reference for the increasing number of cellular organisms with their genomes sequenced. The sTOL builds on a likelihood-based weight calibration algorithm to consolidate NCBI taxonomy information in concert with unbiased sampling of molecular charact...

journal_title：Scientific reports

authors： Fang H,Oates ME,Pethica RB,Greenwood JM,Sardar AJ,Rackham OJ,Donoghue PC,Stamatakis A,de Lima Morais DA,Gough J

更新日期：2013-01-01 00:00:00

abstract：:Polymers have appealing optical, biochemical, and mechanical qualities, including broadband transparency, ease of functionalization, and biocompatibility. However, their low refractive indices have precluded wavelength-scale optical confinement and nanophotonic applications in polymers. Here, we introduce a suspended ...

journal_title：Scientific reports

authors： Gan X,Clevenson H,Tsai CC,Li L,Englund D

更新日期：2013-01-01 00:00:00

abstract：:Asbestos is a potent carcinogen associated with malignant mesothelioma and lung cancer but its carcinogenic mechanisms are still poorly understood. Asbestos toxicity is ascribed to its particular physico-chemical characteristics, and one of them is the presence of and ability to adsorb iron, which may cause an alterat...

journal_title：Scientific reports

authors： Pascolo L,Gianoncelli A,Schneider G,Salomé M,Schneider M,Calligaro C,Kiskinova M,Melato M,Rizzardi C

更新日期：2013-01-01 00:00:00

abstract：:Nitrogen fixation is essential for the synthesis of many important chemicals (e.g., fertilizers, explosives) and basic building blocks for all forms of life (e.g., nucleotides for DNA and RNA, amino acids for proteins). However, direct nitrogen fixation is challenging as nitrogen (N₂) does not easily react with other ...

journal_title：Scientific reports

authors： Jeon IY,Choi HJ,Ju MJ,Choi IT,Lim K,Ko J,Kim HK,Kim JC,Lee JJ,Shin D,Jung SM,Seo JM,Kim MJ,Park N,Dai L,Baek JB

更新日期：2013-01-01 00:00:00

abstract：:The chemiresistive thin film gas sensors with fast response, high sensitivity, low power consumption and mass-produced potency, have been expected for practical application. It requires both sensitive materials, especially exquisite nanomaterials, and efficient substrate chip for heating and electrical addressing. How...

journal_title：Scientific reports

authors： Dai Z,Xu L,Duan G,Li T,Zhang H,Li Y,Wang Y,Wang Y,Cai W

更新日期：2013-01-01 00:00:00

abstract：:We report on a novel electrically tunable hybrid graphene-gold Fano resonator. The proposed metamaterial consists of a square graphene patch and a square gold frame. The destructive interference between the narrow- and broadband dipolar surface plasmons, which are induced respectively on the surfaces of the graphene p...

journal_title：Scientific reports

authors： Amin M,Farhat M,Baǧcı H

更新日期：2013-01-01 00:00:00